What affects musculoskeletal risk in nursing assistants and orderlies?

BACKGROUND: There are many musculoskeletal disorders in staff members at health centres, given the specific characteristics of their work. OBJECTIVE: The objective was to analyse the postural risk of patient handling tasks performed by nursing assistants and orderlies, as well as task factors, individual or organisational, that may be associated with increased postural risk. METHOD: This is a cross-sectional observational study. Analysis was done on 170 postures in five different tasks performed by 39 participants at three hospitals in Andalusia (Spain). The questionnaires collected sociodemographic variables, the task done, and REBA were used for assessment of postural risk. RESULTS: Overall the average REBA score was 9.0±2.4. Moving the patient to the head of the bed was the task with the highest risk (9.8). Handling involving more than two participants at once increased postural risk. Using mechanical aids were associated with high risk in the legs. Logistic regression analyses showed that age, stature, and not having adjustable beds available were associated with postural risk (p < 0.05). CONCLUSION: Health centre staff perform many tasks with high musculoskeletal disorder risk. Age, stature of the participants, and adjustment of bed height were associated with postural risk.

Multi-information source Bayesian optimization of culture media for cellular agriculture.

Culture media used in industrial bioprocessing and the emerging field of cellular agriculture is difficult to optimize due to the lack of rigorous mathematical models of cell growth and culture conditions, as well as the complexity of the design space. Rapid growth assays are inaccurate yet convenient, while robust measures of cell number can be time-consuming to the point of limiting experimentation. In this study, we optimized a cell culture media with 14 components using a multi-information source Bayesian optimization algorithm that locates optimal media conditions based on an iterative refinement of an uncertainty-weighted desirability function. As a model system, we utilized murine C2C12 cells, using AlamarBlue, LIVE stain, and trypan blue exclusion cell counting assays to determine cell number. Using this experimental optimization algorithm, we were able to design media with 181% more cells than a common commercial variant with a similar economic cost, while doing so in 38% fewer experiments than an efficient design-of-experiments method. The optimal medium generalized well to long-term growth up to four passages of C2C12 cells, indicating the multi-information source assay improved measurement robustness relative to rapid growth assays alone.

Pediatric trauma at a general hospital in Cali, Colombia.

BACKGROUND: Trauma is an important cause of morbidity and mortality in children. Blunt trauma is the most common type and falls and road traffic injuries (RTI) are the most frequent mechanisms. METHODS: Secondary analysis of institutional data included within the Panamerican Society of Trauma Registry (STP-ITSDP). A total of 581 trauma patients younger than 18years, hospitalized between 2012 and 2014, were included. RESULTS: Blunt trauma (BT) (68%) was the most common type, and falls (42.5%) the most common mechanism. Median age was: 14years for penetrating trauma (PT), 8years for BT, and 5.5years for other types of trauma (OT). Of all patients, 8.1% had a Glasgow score<8, 9% had a Glasgow score of 8-13 and 81.1% had a Glasgow score higher than 14. Death occurred in 5.2% of patients: 83.3% as inpatients and 16.7% during initial management in the emergency room (ER). Patients dying in the ER were mostly PT victims, with higher ISS and lower Glasgow scores. CONCLUSIONS: Trauma is an important cause of morbidity and mortality in our pediatric population. Fundación Valle de Lili (FVL), a referral hospital, receives a high number of trauma patients from southwestern Colombia. Detailed knowledge of epidemiological data will help us to develop rapid response strategies for patients with trauma and to develop prevention and promotion programs.

[Long-term results of percutaneous mitral valvuloplasty in patients over 50 years old]. / Resultados de valvuloplastía mitral percutánea en pacientes mayores de 50 años y seguimiento a largo plazo.

UNLABELLED: Advanced age has been identified as a predictor factor for complications and poor outcome at Percutaneous Mitral Valvulotomy (PMV) with balloon, nevertheless this has been associated to the inadequate valvular anatomy, whereby the contribution of each factor needs to be determinate. OBJECTIVE: Describe the immediate and final outcome of PMV with Inoue balloon in patients over 50 years old and associate complications with age and Wilkins score. MATERIAL AND METHODS: A retrospective and analytic study was performed with a data base of 430 patients. We included all the patients proceeding from the Centro Medico Nacional Siglo XXI Cardiology Hospital. From January 1996 to December 2005. RESULTS: We selected 137 patients with rheumatic mitral stenosis. We found a Mitral Valvular Area (MVA) before the PMV proceeding of 1.01 cm2 +/- 0.18 and 1.99 cm2 +/- 0.30 post PMV (P < 0.001), with pre procedure transmitral gradient of 14.3 +/- 3.18 mm Hg and of 4.3 +/- 2.6 mm Hg post (P < 0.001). In 128 (93%) the immediate proceeding was considered successful. The Wilkins score was 8.41 +/- 1.31. The observed complications were present in 19 (13.8%), stroke in 3 (2.2%), tamponade in 3 (2.2%), conduction disorder in 5 (3.7%), severe mitral insufficiency in 7 (5.1%), residual interatrial communication in 1 (0.7%). A clinical and echocardiographic follow-up was performed in 113 (83%) MVA was > 1.5 cm2 in 113 at 70 [IBM1] months average, 1.1 to 1.49 cm2 in 14 (10.2%) and < 1 cm2 in 9 (7%). CONCLUSIONS: PMV with Inoue balloon in patients over 50 years old is a procedure with an immediate high successful index and of acceptable risk. We found a restenosis index of 27 (19%) after long follow-up 70 months average.

Resultados de valvuloplastía mitral percutánea en pacientes mayores de 50 años y seguimiento a largo plazo / Long-term results of percutaneous mitral valvuloplasty in patients over 50 years old

Advanced age has been identified as a predictor factor for complications and poor outcome at Percutaneous Mitral Valvulotomy (PMV) with balloon, nevertheless this has been associated to the inadequate valvular anatomy, whereby the contribution of each factor needs to be determinate. OBJECTIVE: Describe the immediate and final outcome of PMV with Inoue balloon in patients over 50 years old and associate complications with age and Wilkins score. MATERIAL AND METHODS: A retrospective and analytic study was performed with a data base of 430 patients. We included all the patients proceeding from the Centro Medico Nacional Siglo XXI Cardiology Hospital. From January 1996 to December 2005. RESULTS: We selected 137 patients with rheumatic mitral stenosis. We found a Mitral Valvular Area (MVA) before the PMV proceeding of 1.01 cm2 +/- 0.18 and 1.99 cm2 +/- 0.30 post PMV (P < 0.001), with pre procedure transmitral gradient of 14.3 +/- 3.18 mm Hg and of 4.3 +/- 2.6 mm Hg post (P < 0.001). In 128 (93%) the immediate proceeding was considered successful. The Wilkins score was 8.41 +/- 1.31. The observed complications were present in 19 (13.8%), stroke in 3 (2.2%), tamponade in 3 (2.2%), conduction disorder in 5 (3.7%), severe mitral insufficiency in 7 (5.1%), residual interatrial communication in 1 (0.7%). A clinical and echocardiographic follow-up was performed in 113 (83%) MVA was > 1.5 cm2 in 113 at 70 [IBM1] months average, 1.1 to 1.49 cm2 in 14 (10.2%) and < 1 cm2 in 9 (7%). CONCLUSIONS: PMV with Inoue balloon in patients over 50 years old is a procedure with an immediate high successful index and of acceptable risk. We found a restenosis index of 27 (19%) after long follow-up 70 months average.

Cardiopatía isquémica aterosclerosa en pacientes con dextrocardia en situs viscerum inversus / Ischemic heart disease in two patients with dextrocardia in situs inversus

Se presentan la incidencia, manifestaciones clínicas, hallazgos radiológicos, electrocardiográficos, ecocardiográficos, gammagráficos y de cateterismo cardiáco de dos casos con la asociación de dextrocardia en situs viscerum inversus con cardiopatía insquémica por aterosclerosis coronaria, así como su evolución clínica y seguimiento a dos años. El primer paciente fue intervenido quirúrgicamente y evoluciona asintomático con prueba de esfuerzo máximo negativa. El segundo paciente, diabético, con anatomía coronaria desfavorable, no fue operado y está en la actualidad con angina estable en clase funcional II de la NYHA. Las características electrocardiográficas y encacardiográficas, y las estrategias angiográficas, son comentadas

Manejo adecuado del Trauma Pediátrico en Colombia: Un reto con Respuestas

Se realizó un estudio descriptivo-retrospectivo en 889 casos de intoxicación de los 33.432 pacientes atendidos entre 1990 y 1991 en el servicio de atención médica de urgencias de la Cruz Roja Colombiana en Santafé de Bogotá. Se presenta globalmente el desarrollo histórico de la toxicología en Colombia y la situación epidemiológica nacional y extranjera. Finalmente se revisa el diagnóstico y tratamiento de los pacientes y se emiten algunas recomendaciones